{"id":1725,"date":"2020-07-18T19:54:36","date_gmt":"2020-07-18T16:54:36","guid":{"rendered":"http:\/\/www.foodlifeculture.com\/en\/?p=1725"},"modified":"2020-07-18T20:32:07","modified_gmt":"2020-07-18T17:32:07","slug":"turmeric-a-new-hope-for-alzheimers-cure","status":"publish","type":"post","link":"https:\/\/www.foodlifeculture.com\/en\/2020\/07\/18\/turmeric-a-new-hope-for-alzheimers-cure\/","title":{"rendered":"Turmeric: A New Hope For Alzheimer\u2019s Cure?"},"content":{"rendered":"<p>Although nature is challenging for all living forms, the miracles it contains are just as many. Mankind, struggling with many diseases from birth to death, is taking important steps every day in order to discover the opportunities that nature offers us to regain health.<\/p>\n<p>Studies on Turmeric in recent years have shown that this spice can prevent brain degeneration, which causes dementia and Alzheimer&#8217;s in later ages, and has led to the emergence of new approaches on treatment methods. Before going into the details of these studies on turmeric, let&#8217;s take a closer look at what Alzheimer is.<\/p>\n<p>In 1906, Dr. Alois Alzheimer identified memory losses and abnormal behaviors especially in elderly individuals, upon examining the causes, he analyzed the brain tissues of patients and found that their brain volumes decreased significantly.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1726 aligncenter\" src=\"http:\/\/www.foodlifeculture.com\/en\/wp-content\/uploads\/2020\/07\/Alzheimer-beyin-atrofisi-e1595090312302.jpg\" alt=\"\" width=\"535\" height=\"555\" \/><\/p>\n<p>In the studies conducted after this process, the causes of Alzheimer&#8217;s have started to be better understood. As the age progresses, the accumulation of <strong>tau proteins and amyloid beta plaques<\/strong> in nerve cells in the brain causes to be impaired the ability of recall and direction. Although there is currently no clear information about why these undesirable substances occur, important clues have been obtained at the point that environmental conditions, stress and genetic factors are important.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1727 aligncenter\" src=\"http:\/\/www.foodlifeculture.com\/en\/wp-content\/uploads\/2020\/07\/Amyloid-beta-42_1IYT-768x444-1-e1595090383940.png\" alt=\"\" width=\"487\" height=\"281\" \/><\/p>\n<p>Amyloid Peptide Plaque<\/p>\n<p>Blennow 2010, Lewczuk 2015, Lame 2011<\/p>\n<p>More than <strong>50<\/strong> million people in the world are reported to have dementia (<strong>Alzheimer&#8217;s<\/strong> is developing in 2\/3 of the patients). This number is expected to reach <strong>76<\/strong> million in 2030 and <strong>133<\/strong> million in 2050. Another upcoming problem is that the elderly population in the coming years has risen with an increasing momentum in the world.<\/p>\n<p>If we come to the situation in Turkey, more than 600 thousand people are known to combat the disease. According to the data of TURKSTAT, the population over 65 years has increased by 21% in the last 5 years and its share in the total population has reached <strong>9%<\/strong> in 2019. With this trend, the rate of elderly population in the population will reach <strong>10%<\/strong> in 2023 and <strong>13%<\/strong> in 2030.<\/p>\n<p>After making this entry about Alzheimer&#8217;s, we can proceed to the research and results on Turmeric.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1728 alignleft\" src=\"http:\/\/www.foodlifeculture.com\/en\/wp-content\/uploads\/2020\/07\/turmeric-root-and-powder-e1595090495804.jpg\" alt=\"\" width=\"259\" height=\"188\" \/><\/p>\n<p>This spice, which is called <strong>turmeric<\/strong>, namely \u201ccastor saffron\u201d, has been used in Asian countries, especially India, for 2500 years. The active <strong>curcumin<\/strong> ingredient has been found, as a result of the studies, it has decreased the rate of catching <strong>Alzheimer&#8217;s<\/strong> by 4.4 times in individuals aged 70-79 compared to America.<\/p>\n<p>&nbsp;<\/p>\n<p>The image below shows a graph of how curcumin reduces <strong>amyloid plaques<\/strong> in mice with Alzheimer&#8217;s. Graph A shows that curcumin prevents these plates from joining together; In the B graph, it means that the plates formed by joining before and the larger pieces were broken.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1729 aligncenter\" src=\"http:\/\/www.foodlifeculture.com\/en\/wp-content\/uploads\/2020\/07\/Amiloid-Tabaka-G\u00f6r\u00fcnt\u00fc-e1595090646658.png\" alt=\"\" width=\"533\" height=\"237\" \/><\/p>\n<p>The image below shows how different amounts of curcumin bind amyloid plaques. In other words, we can state that the graphic given above is a visual representation. Decreases from A to F have been promising for the medical world.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1730 aligncenter\" src=\"http:\/\/www.foodlifeculture.com\/en\/wp-content\/uploads\/2020\/07\/Amiloid-G\u00f6r\u00fcnt\u00fc-2-e1595090717211.png\" alt=\"\" width=\"494\" height=\"330\" \/><\/p>\n<p>Another research area in which <strong>turmeric<\/strong> is the subject is its effect on the immune system. Our macrophage cells are responsible for protecting us by digesting disease-causing microorganisms and other undesirable compounds.<\/p>\n<p>Research conducted at UCLA in 2006 shows that <strong>curcumin<\/strong>, which is the active compound of <strong>Turmeric<\/strong>, has started to clean these plates in the brain by activating macrophage cells.<\/p>\n<p>In the image A., it shows the macrophage cell of an individual with Alzheimer&#8217;s. The bright area around it is the amyloid layers. In the image B., it is seen that the macrophage cell activated with Turmeric cleans the bright area around it.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1731 aligncenter\" src=\"http:\/\/www.foodlifeculture.com\/en\/wp-content\/uploads\/2020\/07\/Amiloid-G\u00f6r\u00fcnt\u00fc-3-e1595090818775.png\" alt=\"\" width=\"561\" height=\"237\" \/><\/p>\n<p><strong>As a result<\/strong>; The positive effects of turmeric on Alzheimer&#8217;s are getting more and more attention in the scientific world. However, it is worth noting that regular use for a long time is important in order to see these positive effects. Although it is beneficial to include this spice in our lives more, we all have to support our brain with active life, additionaly to give up or limit smoking and alcohol and pay attention to what we eat.<\/p>\n<p><strong>References<\/strong><\/p>\n<p><a href=\"http:\/\/www.alzheimerdernegi.org.tr\/haber\/turkiyede-600-000-aile-alzheimer-hastaligi-ile-mucadele-ediyor\/\" target=\"_blank\" rel=\"noopener noreferrer\">Link 1<\/a><\/p>\n<p><a href=\"https:\/\/www.ekonomist.com.tr\/haberler\/tuik-yayimladi-iste-turkiye-2019-yasli-nufus-istatistikleri.html\" target=\"_blank\" rel=\"noopener noreferrer\">Link 2<\/a><\/p>\n<p>Shrikant M. and Palavinelu K. The effect of curcumin (turmeric) on Alzheimer&#8217;s disease: An overview. Annals of Indian Academy of Neurology (2008) 1-13<\/p>\n<p>L. Zhang et al. Curcuminoids and amyloid-\u03b2 uptake by macrophages of Alzheimer\u2019s disease patients. Journal of Alzheimer\u2019s Disease 10 (2006) 1\u20137<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Although nature is challenging for all living forms, the miracles it contains are just as many. Mankind, struggling with many diseases from birth to death, is taking important steps every day in order to discover the opportunities that nature offers us to regain health. Studies on Turmeric in recent years have shown that this spice [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1734,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"amp_status":""},"categories":[60,74],"tags":[43],"_links":{"self":[{"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/posts\/1725"}],"collection":[{"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/comments?post=1725"}],"version-history":[{"count":6,"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/posts\/1725\/revisions"}],"predecessor-version":[{"id":1739,"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/posts\/1725\/revisions\/1739"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/media\/1734"}],"wp:attachment":[{"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/media?parent=1725"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/categories?post=1725"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.foodlifeculture.com\/en\/wp-json\/wp\/v2\/tags?post=1725"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}